Cardiovascular adjustments to acute hypoxemia superimposed on chronic hypoxemia in lambs
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چکیده
منابع مشابه
Cardiovascular adjustments to acute hypoxemia superimposed on chronic hypoxemia in lambs.
Cardiovascular responses to acute hypoxemia are in part mediated through adrenergic and chemoreceptor stimulation. In chronic hypoxemia the response to these stimuli may be blunted. Therefore, we determined whether the cardiovascular responses to acute hypoxemia superimposed on 3-4 wk of chronic hypoxemia were blunted in lambs with an experimental cardiac right-to-left shunt (combination of atr...
متن کاملHypoxemia
تنفس یکی از اساسی ترین نیازهای انسان است که در صورت عدم تأمین این نیاز، حیات انسان چند دقیقه ای بیشتر ادامه نخواهد یافت. اهمیت این فعالیت حیاتی از تأثیر آن بر تغذیه سلولها به عنوان کوچکترین واحد سازنده بدن انسان نشأت می گیرد، زیرا اکسیژن یکی از مواد ضروری برای سلولها می باشد و کسب این ماده حیاتی فقط از طریق تنفس مناسب و راحت امکان پذیر است .
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We studied the effect of pulmonary afferent activity on the heart rate response to a progressive, isocapnic decrease in oxygen saturation (Sao2) in anesthetized rabbits. To abolish the effect of rapidly adapting receptors, we used inhaled bupivacaine aerosol, and to abolish the effect of slowly adapting stretch receptor activity, we used sulfur dioxide insufflation. The heart rate (HR) response...
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The role of normocapnic hypoxemia (arterial PO2 33 +/- 7 torr for 30 minutes) in asphyxial renal failure and its modification by maturation of renal function was studied in 50 chronically catheterized, unanesthetized lambs of 2-38 days postnatal age. Arterial pH and PCO2 did not change significantly in response to hypoxemia in these lambs. Normocapnic hypoxemia was associated with (1) significa...
متن کاملThe effects of chronic hypoxemia on electrolyte and acid-base equilibrium: an examination of normocapneic hypoxemia and of the influence of hypoxemia on the adaptation to chronic hypercapnia.
We have carried out balance studies in normal dogs in order to appraise the effects of chronic hypoxemia on acid-base and electrolyte equilibrium. During the first phase of observation we produced a state of "pure" hypoxemia by reducing the oxygen concentration (utilizing nitrogen as a diluent) and by adding carbon dioxide to the environment in a concentration sufficient to keep arterial CO(2) ...
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ژورنال
عنوان ژورنال: American Journal of Physiology-Heart and Circulatory Physiology
سال: 1995
ISSN: 0363-6135,1522-1539
DOI: 10.1152/ajpheart.1995.268.3.h974